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| Title: |
Carbocisteine Found to Slow Symptoms of COPD (2008) |
| Type： |
New Indication |
| Status： |
Other |
Targeted
Indication(s): |
COPD |
| Developer(s): |
Guangzhou Institute of Respiratory Disease in Guangzhou, China |
Description
/Summary： |
Expectorant carbocisteine seems to help slow worsening of chronic obstructive pulmonary disease (COPD) symptoms, according to Chinese researchers led by Dr. Jin-Ping Zheng, of the Guangzhou Institute of Respiratory Disease in Guangzhou, China.
"Carbocisteine is a highly cost-effective medicine that prevents exacerbation of COPD," Zheng said. Long-term use of carbocisteine can help preserve health-care resources, Zheng said. "This is especially good for developing countries and low-income populations - it provides an option to treat COPD," he said. "Carbocisteine, as well as other mucolytics, are old medicines. However, carefully conducted clinical trials of existing medications can offer new insights into COPD care."
The findings by Zheng's team are in the June 15 issue of The Lancet. For the study, 709 patients with COPD were randomly selected to receive daily doses of carbocisteine or placebo. Over the year of the study, patients receiving carbocisteine had a 25% reduction in the number of exacerbations of COPD, compared with patients receiving a placebo, the researchers found.
"In addition, quality of life was improved significantly," Zheng said, adding that long-term administration of mucolytics, such as carbocisteine, should be recognized as a worthwhile treatment for COPD. |
Additional
Info/Comments: |
n/a |
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