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Dr. Danyi Quan, Chief Scientific Officer of Xel, said, "The failure of recent Phase III clinical trials for AD treatment may cast some new doubt on that theory, as well as on other experimental drugs. In addition, some new Alzheimer drugs show potential risks including serious side effects. However, the clinical studies performed in China to date showed Huperzine A to be more effective than other cholinesterase inhibitors currently on the market, and the U.S. clinical Phase II trials with Huperzine A oral tablets conducted by the nation's leader in AD therapy, Dr. Paul Aisen, clearly demonstrated the efficacy and safety of Huperzine A in the treatment of patients with AD."
"In the past 10 years, there have been limits and some real difficulties in finding a good candidate from existing Western medicines to develop transdermal drug delivery systems. However, many drug candidates derived from botanic sources with proven safety and efficacy data are available for further development, which now has become a fast and effective way for us to select candidates for designing our advanced drug delivery systems. Huperzine A is one of our most promising and successful transdermal products. Its low therapeutic dose and molecular weight makes Huperzine A ideal for transdermal drug delivery. Our once-a-week transdermal patch is a clearly preferable treatment method to AD patients and caregivers. The prototype Huperzine A transdermal patch is ready for IND filing and further development," Dr. Quan added. |